|
| CMN -0001-25 | 26/02/2025 | BD | Permanent | Minor | Launch of New Products in Afghanistan. | Products mentioned in the attached list are not launched in Afghanistan yet. | These products are planned for launch in Afghanistan. | N/A | Approved | 31/05/2025 | In Progress | Nutra | 1)Product Launch in Afghanistan. BD
2)FG codes will be opened. SCM 3) BOM will create on SAP. QA 4) BPR will be prepared. QA
|
| 1)May-25
2)Apr-25
3)May-25
4)May-25
| Hamza Ahmed | 26/02/2025 | Hamza Ahmed | 20/04/2025 |
|
| CMN -0002-25 | 08/04/2025 | PD | Permanent | Major | New launch product Kalsob-M sachet. | Product development activities of generic red algae calcium 1400mg+Vitamin K2 90mcg +Vitamin D3 10mcg+ Magnesium 32mg Sachet has been completed. | It is proposed to commercialize generic red algae calcium 1400mg+Vitamin K2 90mcg +Vitamin D3 10mcg+ Magnesium 32mg Sachet in pharmevo facility. | RA-0015-25 | Approved | | In Progress | Nutra | 01) Trail documents are required. PD
02) Stability study documents are required. PD
03) Technology transfer protocol (for process) is required. PD
04) Technology transfer protocol (for analytical testing) is required. PD
05) Regulatory approval required before commercialization. RA
06) Source approval documents are required. SCM
07) Procurement of red algae calcium raw materials. SCM
08) Artwork will be developed and approved. BD
09) Item codes will be opened for new developed artwork. BD
10) FG codes will be opened. SCM
11) Procurement of packaging material. SCM
12) Analytical testing method will prepared and update on LIMS. QC
13) BOM will be create in SAP. QA
14) Batch documents (BDR, BMR, BYS, and BPR) will be prepared. QA
15) Routing will be create in SAP. Production
16) Planning of product launch for commercial. BD
17) Process validation will be performed. QA(Val)
18) Product will be charge on stability. QC
|
| 1) Oct-25
2) Oct-25
3 Oct-25
4) Oct-25
5) Oct-25
6) July-25
7) Sep-25
8) Oct-25
9) Oct-25
10) Aug-25
11) Nov-25
12) Nov-25
13) Nov-25
14) Nov-25
15) Dec-25
16) Dec-25
17) July-26
18) Aug-26
| Hamza Ahmed | 14/04/2025 | Hamza Ahmed | 19/08/2025 |
|
| CMN -0003-25 | 07/05/2025 | BD | Permanent | Minor | Launch of New Products in Uzbekistan. | The products mentioned in table is not launched in Uzbekistan yet. S.No 01
Product Femova Sachet
Generic Myoinositol + D-Chiroinositol + Quatrefolic
Pack Size 10's
Shelf Life 24 months
Registration Timeline Jun-25
Pack size in Local 10's (For reference only) | This product is planned for launch in Uzbekistan. | | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 07/05/2025 | Hamza Ahmed | 08/05/2025 |
|
| CMN -0004-25 | 22/05/2025 | Production | Permanent | | Installation of 200Kg double cone blender in production nutraceutical building | Currently we have 100kg double cone blender in production nutraceutical building | It is proposed to install another 200kg double cone blender nutraceutical building | N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 22/05/2025 | | |
|
| CMN -0005-25 | 23/05/2025 | BD | Permanent | | Launch of new product in Kyrgyzstan | The product mentioned in the attached list are not launch in Kyrgyzstan. | These products are planned to be launched in Kyrgyzstan. | N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 23/05/2025 | | |
|
| CMN -0006-25 | 23/05/2025 | BD | Permanent | | Launch of Additional Pack Size of Product in Tajikistan. | The below mentioned product is already launched in the mentioned pack size in Tajikistan.
S.No : 01
Product : Femova Sachets
Generic : Myoinositol 1100mg + D-Chiroinositol 300mg + Folate 600 mcg as (6S)-5-MTHF
Pack Size : 1x10's
Shelf Life : 24 Months
Registration Timeline : Registered
| It is proposed to Launch below product in mentioned pack size in Tajikistan.
S.No : 01
Product : Femova Sachets
Generic : Myoinositol 1100mg + D-Chiroinositol 300mg + Folate 600 mcg as (6S)-5-MTHF
Pack Size : 3x10's
Shelf Life : 24 Months
Registration Timeline : Registered
| N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 23/05/2025 | | |
|
| CMN -0007-25 | 23/05/2025 | QA | Permanent | | Incorporation of a Precautionary Statement "Do not handle the tablets with wet hands" on SheVit Tablets Packaging Components. | Currently, the packaging components of SheVit Tablets (carton, label, and leaflet) do not include any precautionary statement advising users on the proper handling of the tablets to prevent physical degradation due to moisture exposure. | Addition of the following precautionary statement to the packaging components (carton, label, and leaflet) of SheVit Tablets:
• English : Do not handle the tablets with wet hands
• Urdu : ?????? ?? ???? ?????? ?? ?? ??????
| N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 23/05/2025 | | |
|
| CMN -0008-25 | 23/05/2025 | SCM | Permanent | | Additional source induction of VITAMIN C (ASCORBIC ACID) COATED 97% | We are currently procuring Excipient: Vitamin C (Ascorbic Acid) Coated 97% from SUPREEM PHARMACEUTICALS MYSORE PVT LTD, INDIA | We intend to induct one more source M/s. LUWEI PHARMACEUTICAL GROUP CO LTD. Add: SHUANGFENG INDUSTRIAL PARK, ZICHUANDISTRICT, ZIBO CITY SHANDONG, CHINA | N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 24/05/2025 | | |
|
| CMN -0009-25 | 29/05/2025 | Production | Permanent | | Increases in Batch sizes of products | Currently, the following products are available in different batch sizes, but they are not sufficient to meet market demand. | It is proposed to increase the batch sizes of products mentioned below:
1 Kalsob tablet.
2. K-1000 Chewable tablet.
3. Ferfer sachet.
Detailed document is attached with details related to number of lots, increased batch size and equipment.
| N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 29/05/2025 | | |
|
| CMN -0010-25 | 29/05/2025 | Production | Permanent | | Inclusion of primary packaging material (A/F) in Manufacturing Orders for Sachet Products (Nutraceutical Sachet Area).
| Currently, the primary packaging material (Aluminum foil) for sachet products are part of the Packaging Order process. A/F is issued after the completion of the manufacturing process. | It is proposed to include the primary packaging material (Aluminum foil) into the Manufacturing Order, aligning the Aluminum Foil issuance with the dispensing of raw materials. Dispensing procedure will remain same for raw and packaging material.(List of sachet product is attached) | N/A | under Approval | | | Nutra |
|
|
| Hamza Ahmed | 29/05/2025 | | |
|
| CMN -0011-25 | 24/06/2025 | QC | Permanent | | Reduce testing for Nutraceutical product (Shevit) | | | | | | | Nutra |
|
|
| Hamza Ahmed | 25/06/2025 | | |
|
| CMN -0012-25 | 30/06/2025 | QA | Permanent | | Induction of new instrument weighing balance MA-204 Mettler Toledo with printer in QA IPC Lab Nutra. | Currently no weighing balance is available in IPC Lab Nutra. | Induction of new instrument weighing balance MA-204 Mettler Toledo with printer in QA IPC Lab Nutra. | | | | | Nutra |
|
|
| Hamza Ahmed | 30/06/2025 | Hamza Ahmed | 08/11/2025 |
|
| CMN -0013-25 | 04/09/2025 | PD | Permanent | Major | Change in Coating material of SheVit Tablet. | Currently, Insta Moistshield White Aqua II is being utilized as the film coating material. This material was initially introduced as an alternate source in place of Opadry AMB II. However, maintaining a consistent inventory has become challenging, due to its Indian origin and current going political situation in the region. | It is proposed to replace Insta Moistshield White aqua II with Opadry AMB II as the coating material.
Addition of colorant in seal coating stage.
Increase in the percentage weight gain of the tablets during both coating stages. | N/A | Approved | | In Progress | Nutra | 01) SFG BOM will be revised in SAP. QA
02) BDR & BMR will be revise. QA
03) Testing method and LIMS specification will be revised. QC
04) Process validation will be performed. QA (Val)
05) Stability will be performed on validation batches. QC
|
| 1) Oct-25
2) Oct-25
3) Oct-25
4) Feb-26
5) Feb-26
| Hamza Ahmed | 11/09/2025 | Hamza Ahmed | 18/09/2025 |
|
| CMN -0014-25 | 19/09/2025 | Production | Permanent | Major | Addition of ZP23D Compression machine in nutra facility | Currently compression process of Kalsob tablet is being carried out on ZPW20 compression machine. | It is proposed to add compression machine ZP23D for the compression process of Kalsob tablet. | N/A | Approved | | In Progress | Nutra |
|
|
| Hamza Ahmed | 22/09/2025 | Hamza Ahmed | 01/10/2025 |
|
| CMN -0015-25 | 23/09/2025 | QC | Permanent | Major | Reduce testing for Nutraceutical products (Kalsob Tablet, K-1000 Tablet, Ferfer Sachet and Ferfer Gro Sachet) | QC is carrying out complete testing of the following nutraceutical products at the Pharmevo, KAlsob Tablet, K-1000 Tablet, Ferfer Sachet and Ferfer Gro Sachet. | It is suggested to perform reduced QC testing for the above mentioned nutraceutical products in PharmEvo. | N/A | Approved | | In Progress | Nutra |
|
|
| Hamza Ahmed | 23/09/2025 | Hamza Ahmed | 03/10/2025 |
|
| CMN-0016-25 | 30/09/2025 | SCM | Permanent | | Additional source induction of Coenzyme Q10 | We are currently procuring Nutraceutical material Coenzyme Q10 from M/s. 1. Weihai Nutraway Pharmaceutical Co Ltd & 2. Sirio Pharma Co. Limited. | We intend to induct one more source M/s Shaanxi Healthful Bioengineering Co., Ltd, Address: HSF Industrial Park, Chuang Xin Road, Yangling Demonstration Zone, Shaanxi Province P.R. China | | Under Approval | | | Nutra |
|
|
| Hamza Ahmed | 30/09/2025 | Hamza Ahmed | 30/09/2025 |
|
| CMN-0017-25 | 24/11/2025 | SCM | Temporary | | Change in master carton of shevit and K-1000 tablet. | Currently master carton, M/C (MC-08) is being used in shevit and M/C (MC-30) is being used in K-1000. | We have following white 5 ply master carton in inventory which needs to be consumed in Shevit and K-1000 tablets as mentioned below:
Product: Shevit Tab. CP 1x30's. Existing Master Carton: M/C (MC-8). Code Existing Master Carton: M/C (MC-08) 5ply Coated Paper White. Code Master Carton to Consume: 1200000673. Available Qty: 7,593. Qty/ batch: 67. No of batches to consumed inventory: 113
Product: K-1000 Tab. CP 1X30's. Existing Master Carton: M/C (MC-30). Code Existing Master Carton: 1200000688. MAster Carton to Consume: M/C (MC-30) 5ply Coated Paper White. Code Master Carton to Consume: 1200000689. Available Qty: 3,439. Qty/ batch: 67. No of batches to consumed inventory: 51.
After consumption of available stock of 5 ply master carton, BOM will be revert to existing master cartons as mentioned in above chart.
Procurement of 5 ply master carton will be blocked to avoid reordering in future. | | | | | Nutra |
|
|
| Hamza Ahmed | 24/11/2025 | Hamza Ahmed | 25/11/2025 |
|
| CMN-0018-25 | 25/11/2025 | QA | Permanent | | Removal of Flip-Off from Cap (Cap Type Modification) of Shevit Tablet Bottle. | Currently, Shevit Tablet bottles are sealed withj flip-off cap. the cap includes an outer flip-off cover along with standard cap in purple color. | To discontinue the use of the flip-off from the cap, while keeping all other specificatopns unchanged, including cap color (purple), material (PET), and dimensions. | | | | | Nutra |
|
|
| Hamza Ahmed | 25/11/2025 | | |
|
| CMN-0019-25 | 25/11/2025 | PD | Permanent | | Change in formulation and revised artwork of Femova Sachet. | Currently, Femova Sachet is being manufactured as per the formulation attached in annexure I. | It is proposedto revise formulation of Femova Sachet by replacing citric acid and sodium citrate with ascorbic acid and aspartame with sucalose. Butylated hydroxyanisole is also added in formulation as mentioned in Annexure I.
Orange Durarome Flavour 858024TBB0594 will be used with 20% less quantity as per CMN-0008-24.
Artwork to be revised mentioning storage condition as "Store below 25C." | | | | | Nutra |
|
|
| Hamza Ahmed | 25/11/2025 | | |
|
| CMN-0020-25 | 25/11/2025 | PD | Permanent | | Change in formulation of K-1000 Chewable Tablet. | Currently, K-1000 Chewable Tablet is being manufactured by Calcium Carbonate 92.5%, Xylitab 200 and Aspartame as per formulation attached in annexure I. | It is proposed to replace Calcium Carbonate (92.5)% and aspartame with Calcium Carbonate (95%) and sucralose, respectively. Additionally, mannitol (Pearlitol) will be incorporated as mentioned in the formulation attached in Annexure I. | | | | | Nutra |
|
|
| Hamza Ahmed | 25/11/2025 | | |
|
| CMN-0021-25 | 22/12/2025 | QC | Permanent | Minor | | | | N/A | Approved | | | Nutra |
|
|
| Hamza Ahmed | 22/12/2025 | | |
|
| CMN-0022-25 | 23/12/2025 | SCM | Permanent | | Additional source induction of Excipient for Nutra Products: Mannitol (Pearlitol). | We are currently procuring Excipient for Nutra Products: Mannitol (Pearlitol) from one approved manufacturer M/s. Roquette France. | We intend to induct one more source M/s. Shijiazhuang Huaxu Pharmaceutical Co. Ltd.
Address: No.33 Industrial Street, Economic Development Zone, Shijiazhuang City, Hebei, China. | | Under Approval | | | Nutra |
|
|
| Hamza Ahmed | 23/12/2025 | | |